Santiago to La Serena Trip Overview
Distance 398 km (248.8 miles) | |
Price range US$ 15-US$ 60 | |
Ride Duration Range 4h-11h 56m | |
Earliest Departure 11:30 | |
Latest Departure 23:30 | |
Most Popular Operator |
Find up-to-date information on departure times, schedules, and prices so you can easily compare and book your tickets.
Taking a bus from Santiago to La Serena
Fastest bus: 4h
Cheapest bus: US$ 15

About the ride from Santiago to La Serena
Santiago to La Serena Route Information
The distance between Santiago and La Serena is 249 miles, or approximately 398 kilometers.
There are 2 ways to get from Santiago to La Serena, including bus,flight.
The earliest departure leaves at 11:30 and has a duration of 6 hours 10 minutes.
The fastest way to travel is by bus, which takes approximately 4 hours.
Santiago to La Serena by bus
- Starting Price: US$ 15
- 535 departures a day, or 3745 departures a week
There are 19 travel classes for this journey, including: Sleeping, Premium Sleeping, Semi-Sleeper, Express, Premium Class, Private Sleeper, VIP 32 Seats, Low Cost Semi Sleeper, Low Cost Sleeper, Single Sleeper Premium, Single Sleeper, Standard, Sleeper, Suite Premium, Economy Sleeper, Semi Sleeper Premium, Economy Semi Sleeper, Premium and Single Suite Sleeper.
Each bus ticket offers an individual seat with basic passenger necessities. Conditions and amenities vary by provider. For more detailed information and availability see all bus options.
Santiago to La Serena by flight
The only travel class available is Economy.
Each flight ticket offers an individual seat with basic passenger necessities. Conditions and amenities vary by provider. For more detailed information and availability see all flight options.
Companies Operating from Santiago to La Serena
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