Getting from Santiago to La Serena
Compare all buses, starting from 12$
Google Play
4.5
App Store
4.4
yotpo.
4.7
Bus from Santiago to La Serena
Bus
Compare bus options from Santiago to La Serena across 12 operators.
Optional amenities
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About this route
- The distance between Santiago and La Serena is 398 km (248.8 miles)
- Buses are the best way to travel between Santiago and La Serena. They are usually the most affordable option and typically depart from central bus stations.
- 12 operators run this route, with prices from 12 US$.
- Journey times range from 5h 40m to 6h 48m depending on the operator and stops.
- Departures run throughout the day, so booking on short notice is usually possible, but availability changes with the season.
Route shown is for illustrative purposes only. Exact routing depends on your selected operator.
Companies Operating from Santiago to La Serena
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