There are 2 operators that run from Rome to Catania, with 2 departures per day. If you decide to take a Bus, you can take the Standard option.
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Read moreBookaway's customers prefer Standard Bus by Autoservizi Salemi
Standard Bus by BusCenter which usually takes 10h
BUS: Autoservizi Salemi | BusCenter
536 Km (Air)
Standard Bus by BusCenter starting at US$79
Approximately, there are 2 departures each day.